COOL Prime Study

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www.coolprime.org

COOL Prime (Comparative Effectiveness for Cooling Prospectively Infants with Mild Encephalopathy) is an observational study that will look at the effects of therapeutic hypothermia (TH) vs normothermia (NT) in infants with mild hypoxic ischemic encephalopathy (HIE). The choice of therapy will be based on each clinical site’s existing practice.